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The mRNA level of LPL increased in the carnitine supplementation group in the liver in the feeding state but decreased in the muscle in the fasting state (Fig

Mouse strains C57BL/6J mice were obtained from Janvier Labs (Le Genest-Saint-Isle, France)

Plus, L-Carnitine helps support blood flow to the muscles, delay muscle fatigue and decreases soreness after intense exercise

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Furthermore, three-dimensional culture studies showed that CPT1A is upregulated in tumor cells within adipose tissues compared to that not in direct contact with adipocytes, whereas CPT1A silencing reduces tumor organoid formation and downregulates genes associated with cancer stem cells