nadph oxidase glutathione Pathways Glutathione-Related Enzymes and Proteins: A

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gesehen bei viralen Infektionen, AIDS, Malignomen, Xenobiotika/-Schwermetallbelastung, Arteriosklerose (Lipidperoxide, erkennbar am erhhten MDA-LDL!), einigen Autoimmunerkrankungen (SLE, rheumatoide Arthritis) sowie neuro-degenerativen Erkrankungen

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For example, in cerebral ischemic stroke, brain tissue exhibits varying patterns of cell death based on ischemic duration, oxygenation levels and residual blood flow (96,97)

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GSH depletion cause indirectly formation of endotoxins in the cytoplasm of pigmented SN cells that contribute to the degeneration of these neurons in PD Figure 2. As previously mentioned the activity of -GT is up-regulated significantly in the parkinsonian SN [61]