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335 Quercetin, which targets the Bcl-2 family member hypoxia-inducible factor-1 (HIF-1) and the antiapoptotic PI3K/AKT and p21 signaling pathways, has demonstrated synergistic effects (Table 1)

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So, knowing that, what exactly are the benefits associated with orange essential oil

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In addition to this, it has further been demonstrated that OS can cause direct DNA damage in spermatozoa, which results in the disruption of chromatin integrity and the consequent reduction in fertilisation potential [13, 26]

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Ligandin: a hepatic protein which binds steroids, bilirubin, carcinogens and a number of exogenous organic anions

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Maor S, Yosepovich A, Papa MZ, Yarden RI, Mayer D, Friedman E, et al

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