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B12 can help with fatigue related to anemia due to its blood-building benefits, as well

J Urol 129:12041206

Hydroxocobalamin (Vitamin B12) Injection Hydroxocobalamin (Vitamin B12) Injection (10 mL Vial) Product Overview Hydroxocobalamin (Vitamin B12) Injection is a compounded sterile solution of hydroxocobalamin, a form of vitamin B, typically supplied at a concentration of 2 mg/mL in a 10 mL vial

These include drugs affecting blood cell production (chloramphenicol, anticancer or HIV drugs) and other vitamin and mineral supplements (especially folic acid)

Vitamin B12 plays a role in this process by supporting hormonal balance