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realized that hydrolysis of the thiosuccinimide ring prevented this elimination
Similarly, the administration of sunitinib in a human glioma model resulted in a decrease in MVD and collagen IV density (but no effect on -SMA density) and an improvement in tamizolomide penetration into brain tumors (81,82)
It has no EMA marketing authorization and is not listed in the Community Register of medicinal products
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Smith RA, Porteous CM, Gane AM, Murphy MP
