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5 Effects of microgravity on intestinal barrier Microgravity is the predominant characteristic of the space environment, which can induce physiological adaptation and pathophysiological alterations in multiple systems, such as muscle atrophy, bone demineralization, and immune system dysregulation (Nie et al., 2024)

Targeting MTHFD2 to exploit cancer-specific metabolism and the DNA damage response

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10.1158/0008-5472.CAN-11-3605 283 Van Der KnaapJ

, Chen, G

Many of these agents are not approved by the FDA for musculoskeletal indications and may be compounded or sourced outside regulated pharmaceutical manufacturing pathways