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Dehydroepiandrosterone (DHEA) may inhibit mitophagy via suppression of AMPK/SIRT1 pathway (Ma et al., 2024)
Biliary lipid analysis can highlight a modestly reduced biliary salt content [1, 2, 41, 42]
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This impairs capillary integrity, allowing peripheral iron, lymphocytes, and cytokines to infiltrate the brain parenchyma, thereby amplifying local inflammation and iron dysregulation (Chen X

10.1016/j.neurot.2025.e00600 14 ChenY.LuY.WangY.DingN.HuangZ.HuJ.et al (2025b)

The role of early pregnancy maternal selenium levels on the risk for small-for-gestational age newborns

Nevertheless, the complex pathophysiology of post-MI tissue remodelingencompassing inflammation, fibrosis, and electromechanical dysregulationposes critical limitations for single-target intervention approaches