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In vivo, DFO also shows cardioprotective effects by inducing ischemic preconditioning-like effects in I/R models, and reduction of mice atherosclerotic lesion by inhibiting inflammation and impairing nitric oxide action [112,113,114]

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Early microstructural alterations could be determined based on variations in fractional anisotropy scores in the SN, striatum, and thalamus substrate nucleus vary in DTI images of PD patients (Pyatigorskaya et al., 2017)

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To assess the GSSG fraction, first, thiol groups of GSH are blocked with N-ethylmaleimide (NEM) in a subsample, followed by removal of excess NEM with toluene prior to reduction of GSSG to GSH with DTT and derivatization via mbrB (Kranner 1998

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