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At physiological levels, BCAAs enhance CD8 + T cell antitumor activity via FoxO1-mediated glucose transporter 1 (GLUT1) upregulation, facilitating glycolytic-oxidative phosphorylation coupling (Yao et al., 2023)

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7 Glutathione-mediated regulation of NF-B, MAPK, and PI3K/AKT pathways in cancer progression and metastasis The NF-B, MAPK, and PI3K/AKT pathways are key regulators of tumor growth, resistance to oxidative stress, and metastasis, operating through redox-sensitive signaling mechanisms

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Histological and immunohistochemical analysis of the thyroid showed that after the exposure there was a relative increase in the appearance of follicles at rest with a consequent decrease in the number of active follicles, in addition to the appearance of macrophages, dilated follicles and flattened epithelium, with decreased volume of colloid

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