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Interestingly, mutations compromising NADPH production in humans or mice are often non-lethal, although compensatory pathways remain only partially understood 4,5

Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells
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Rodrguez ML, Prez S, Mena-Moll S et al (2019) Oxidative stress and microvascular alterations in diabetic retinopathy: future therapies

The role of cell death in SARS-CoV-2 infection
