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Research from Hokkaido University published in Cell Metabolism showed NNMT enzyme activity suppression peaked at specific tissue concentrations

Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA

It thus may not be misbranded, misused, or mislabeled as a drug

Note how the same serum samples yields different results depending on the specific method (= Brand) used (left panel), and with the same method (right panel)

The documented pattern is simply a steady daily presence of the inhibitor, held long enough for the downstream metabolic change to accumulate