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Saaddine, J
Superior antitumor immunotherapy efficacy of kynureninase modified CAR-T cells through targeting kynurenine metabolism

CJC-1295 without DAC (often called Modified GRF 1-29) has a much shorter half-life of around 30 minutes

10.3390/molecules23102474 Molecules 152 VeenmanL.PapadopoulosV.GavishM

As a result , investigators focus on mechanistic pathways and molecular interactions rather than clinical effects

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