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During the animal termination procedure, rats were anesthetized for tissue perfusion and then euthanized for tissue collection

It is important to remember that supplements like NAC are most effective when integrated into a comprehensive, holistic management strategy

Moreover, IGF-IR interacts with discoidin domain receptors, the non-integrin collagen receptors that promote EMT, cell proliferation, and survival [59, 60]

Neurosci 162:12121219

This results in the upregulation of inflammatory molecules such as IL-6 and TNF-, which promote chronic inflammation and further enhance the SASP

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