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Discovery of a glutathione utilization pathway in Francisella that shows functional divergence between environmental and pathogenic species

This involves the use of radionuclides emitting particles, like 225 Ac, 212 Pb or 211 At, and -particles like 90 Y, 131 I, or 177 Lu, to exert cytotoxic effects

& Chewapreecha, C

To reveal the intricate interaction between cell energy metabolism and ferroptosis in senescent germ cells, Lin et al

Pyroptosis of breast cancer stem cells and immune activation enabled by a multifunctional prodrug photosensitizer

In summary, the clinical potential of CAR-M therapy is becoming evident, while targeting key nodes in macrophage polarizationsuch as Furin, PAD4, and PGAM5and their combination with existing therapies like PD-1 inhibitors are opening new avenues for enhancing anti-tumor immune responses