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High homocysteine has also been linked to migraines

Immunity 50 , 432445.e437 (2019)

doi: 10.3945/jn.113.180794
doi: 10.1254/jphs.fp0061533

But by age 80, blood levels have dropped 95%, to about 10 to 20% of what they were at age 20

A single contaminated vial means throwing away weeks of supply
