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This study is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines [15]

These molecules use chemical cross-links to stabilize peptide structure and improve cell permeability while maintaining biological activity

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Vitamin B12 injections are a common treatment for patients with a proven B12 deficiency or specific medical needs, and when administered appropriately, these injections are considered safe and effective

Prenatal vitamin supplements available in the UK contain varying amounts of B12, typically ranging from 2.5 g to 20 g or more, which exceeds the daily RNI

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