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The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure

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An interesting example is the healing of duodenocolic fistulas in rats through BPC 157 therapy very early upon the creation of a duodenocolic fistula [169]

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