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Enhanced elastase activity and elastin-derived peptides act chemotactically, contributing to both the increase in the inflammatory cellular infiltrate and the influx of fibroblasts [20]

It can be speculated that, in a condition of high aggressiveness, typical of GBM, an increase of carnitine cell content is required to sustain the high energy demand of cell proliferation

However, the majority of patients in literature presents in adolescence or adulthood with myopathy as first complaint [106]

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PMID: 17097761