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2 Next-generation redox-adaptive nanoplatforms: insights from recent breakthrough studies Recent work has rapidly advanced organelle-targeted, microenvironment-activated nanomedicines that directly intersect with glutathione (GSH)-responsive sensing and therapeutics Table 1

Administering AFB1 was shown to lead to severe injuries, cardiotoxicity of cardiomyocytes, impairment of mitochondrial functions, increased production of reactive oxygen species, and apoptosis (48)

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NAC is particularly effective in enhancing the body's detoxification processes

8a), indicating that while the Cagri-CTR complex can sample this conformation, it occurs at lower frequency than rAmy-CTR