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doi: 10.1002/jcla.23969 30 AhmedSMahonyCBTorresAMurillo-SaichJKembleSCedenoMet al

The assay was completed in PBS (pH 7.4) as assay buffer with 0.1% BSA and 0.01% Tween-20 added to reduce nonspecific interactions and 2% DMSO added to increase compound solubility

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We hope that the results of our pre-clinical studies will provide the basis for future clinical trials where the HGF and Met inhibitors could synergize with current therapies to increase survival and improve the quality of life of children with brain tumors

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