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Acknowledgements The work of the authors is supported by a Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science 24390213 (M

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(2021) used the THP-1 differentiated macrophages line to assess the cytotoxicity of cynaroside

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Int J Mol Sci 22(13):7017 Parackova Z, Zentsova I, Bloomfield M et al (2020) Disharmonic inflammatory signatures in COVID-19: augmented neutrophils but impaired monocytes and dendritic cells responsiveness

It also promotes hair growth and contributes to overall beauty