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Beyond the experimental findings, these results have relevant public health implications for the Amazon region, where chronic Hg exposure remains a major concern due to environmental contamination and dietary habits
doi: 10.1038/s41598-022-23906-2
However, the performance of Tbr1 +/ mice provisioned with the 1/4 cocktail supplement was comparable to that of their WT littermates (Fig 8E)
The allosteric inhibitor site binds ATP essentially only when the enzyme is in the T state
The GSH/GSSG ratio is widely recognized as a sensitive indicator of oxidative stress (Kern & Jones, 2006
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