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Notably, pro-inflammatory cytokines and kynurenine pathway metabolites can induce ROS bursts, leading to additional damage to glial cells and aggravating neuronal injury, thus establishing a harmful cycle that accelerates neurodegeneration (Wu et al., 2021)

& Hong, W

Not surprisingly, the alternative oxidase pathway can be activated by cold temperatures

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Carlsson, P

115 LiuC.KueiC.ZhuJ.YuJ.ZhangL.ShihA.et al (2012)
