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C., Petzinger, G

Rodriguez-Manzaneque, M

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1C, D, Fig

GC is commonly treated with surgery (Mihmanli et al., 2016)
The remodeled microbiome composition further optimizes the integrity and permeability of the intestinal barrier via Occludin, ZO-1, Claudin-2, and Mucin 2 (MUC2), at the same time suppressing the activity of M1-type macrophages, thereby improving the clinical indices of bone health, including BMD, BV/TV, and Tb