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Genetic models are useful to study dysfunctions of myelination and axonal transport but they are not suitable to investigate remyelination

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Weakened tendons can also be caused by diseases that disrupt blood supply, including: Chronic kidney failure High cholesterol Inflammatory diseases (rheumatoid arthritis, systemic lupus erythematosus) Diabetes mellitus Infection Metabolic disease Surgery Previous surgery around the tendon, such as a total knee replacement or anterior cruciate ligament reconstruction, might put you at greater risk for a tear

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[20] Another study in aging rats demonstrated extension of life span for rats subjected to constant illumination or to a natural light regimen typical of northern regions