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Targeting Mediators/Survival Factor Interleukin-6 Receptor Inhibition Interleukin-6 (IL-6) is a pleiotropic cytokine produced by many different cell lineages

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Similarly, S-nitrosylation of serine racemase inhibits the formation of the NMDA receptor coagonist, D-serine, which would decrease NMDA receptor activity [301]

However, on depletion of antioxidant capacity, NO exacerbates neuroinflammation, which may aggravate AD in patients [4,5,6,7]

[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Ndisang J.F