most common place for melanotic macule macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Oral Melanotic Macule: a small

INTRODUCTION The melanocortinergic (MC) system mediates a wide and complex array of physiological effects including skin pigmentation, salt regulation, food intake regulation, pain nerve regeneration, sexual behavior and penile erection [1-5]

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fereuncinata B

This happens when your body is in a fluid deficit, and can occur because you're either not consuming enough fluid or you're losing too much (via NHS Inform)

CCS can be difficult to distinguish from metastatic melanoma based solely on histology and immunohistochemistry (IHC) because of the significant overlap between them