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In contrast, high heteroplasmy levels impair tumorigenesis due to the collapse of oxidative phosphorylation (OXPHOS)

Serum and liver vitamin B12 concentrations were found to be significantly elevated for 24 days in lambs treated with a single 2 mg subcutaneous vitamin B12 injection, compared to untreated controls ( There have also been a few case series published reporting the general efficacy of the subcutaneous route at normalising plasma B12 levels

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The Journal of Maternal-Fetal & Neonatal Medicine, 31 (9), 11281136