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To confirm the occurrence of ferroptosis, renal tissue sections were stained at various time points to detect the 4HNE levels, which is an end product associated with ferroptosis

Butyrate is directly used by the cell lining the gut for energy

Quercetin has been widely studied because of its strong anti-inflammatory and antioxidant properties, including inhibiting the production of inflammatory factors, tuning immune cell infiltration and suppressing oxidative stress) (17-24)

In this method, it is necessary to activate the ligand and/or the support first

These biotransformation processes by HBMEC may facilitate metabolite elimination from brain or, on the other hand, such modifications may enhance retention or assist further uptake and delivery to other neuronal cell types, therefore spreading their beneficial effects

This weakness of intestinal barrier might make ASD patients more vulnerable to environmental pathogens