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the drugs being used to construct ADCs include, but are not limited to microtubule inhibitors and DNA-damaging agents, polymerase inhibitors e.g
10.1016/j.nbd.2006.10.007 [DOI] [PubMed] [Google Scholar] Hong S.-Y., Gil H.-W., Yang J.-O., Lee E.-Y., Kim H.-K., Kim S.-H., et al
To extend the lifespan, most mitochondrial manipulations should be applied before adulthood 37
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McKernan et al , 1991)
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