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Gastrointestinal obstruction have been reported in the prp-TDP-43 A315T mouse line 74

The most recent therapies involve human embryonic stem cell (hESC)derived RPE cell suspension transplantation

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In contrast, astrocytes with activated NF-B (sham GoF) already showed a prominent decrease in cAEG gene expression, which was further aggravated after TBI (Fig

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It suppressed iNOS and NF-B activation in glial cells, prevented astroglial and microglial oxidative injury in ex vivo systems, and inhibited microglial activation in lipopolysaccharide (LPS)induced Parkinsons disease (PD) models (Wang et al., 2002)