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Glutathione and Liver Detox Glutathione plays a very important role in the detoxification functions of the liver and in the control of the thiol/disulfide exchange in the cells

Detailed mechanism-based in vitro and in vivo studies should be performed for the characterization of their possible pharmacological effects

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Pharmacokinetic models are mathematical concepts used to predict plasma concentrations of drugs at different time points

Activation of PI3K/Akt signaling pathway leads to phosphorylation and inactivation of GSK-3, 335 subsequently activating Wnt/-catenin signaling 336 and exerting a protective effect against cerebral I/R injury 337 (Fig

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