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Germain I, Tetu B, Brisson J, Mondor M, Cherian MG: Markers of chemoresistance in ovarian carcinomas: an immunohistochemical study of 86 cases

The classification covers IGF-1 in all forms native, recombinant, and engineered analogs

Key contributions include the identification of natural compounds, such as epigallocatechin gallate (EGCG) and forskolin, which offer neuroprotective and intraocular-pressure-lowering benefits, and the development of novel drug molecules like Uparant for retinal neovascularization

These differences may have resulted in a relative reduction in effect sizes when pooling cross-sectional estimates obtained in the main analyses and those from 6-year follow-up analyses

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The activity of IGF-1 is in part regulated by its binding proteins