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Cargo recognition and degradation by selective autophagy

Assuming equivalent efficacy across routes requires assumptions about bioavailability that aren't currently supported by direct comparative data

Split Dosing Option Some protocols call for splitting the daily dose into two administrations, typically morning and evening

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The primary targets and mechanisms involved in BV's anticancer actions include the PI3K/Akt/mTOR pathway (e.g., PI3K, Akt, and mTOR), apoptosis signaling pathway (e.g., EGFR and TNF-, including downstream effectors like Casp-3, Casp-7, Casp-8, Casp-9, Bcl-2, Bax, and Bcl-xL), and p38 MAPK pathway

Most side effects are mild and injection-related