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Furthermore, the observational nature of the study precludes conclusions regarding causality between UGCR and disease progression

The latter possibility, however, appears unlikely, since in line with the assumption that the thiol oxidation is catalyzed by the enzyme-bound Cu 2+ , CSH (similarly to other thiols) was incapable of extracting metal ions (Cu 2+ or Zn 2+ ) from the active site of holo-SOD1 WT (Fig

Pharmacol Rev (2004) 56(2):16384

Excessive ROS generation near lipid membranes, combined with free iron, facilitates lipid peroxidation (LPO)

Salidroside Mediated the Nrf2/GPX4 pathway to attenuates ferroptosis in Parkinsons disease

Physiol Plant 128(1):4857 Li H, Han JL, Lin J, Yang QS, Chang YH (2015) A -glutamylcysteine synthetase gene from Pyrus calleryana is responsive to ions and osmotic stresses