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Structural models of SjTGR, SjTrx1i, and SjTRP14 were generated using AlphaFold2 for the structure determined by molecular replacement with PHASER [50]

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This is consistent with the increased yAP1dependent TRX2 transcription previously described for a trr1 mutant (CarmelHarel & Storz, 2000)

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This requires the p53 transcriptional target cyclin-dependent kinase inhibitor 1A (encoding p21) and is associated with slower depletion of intracellular glutathione and decrease accumulation of toxic lipid-ROS (143)