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The first line of antioxidant defense against ROS is very efficient and is predominantly represented by the intracellular antioxidant pool, consisting of antioxidant enzymes, including Cu,Zn-SOD (SOD1), catalase, glutathione peroxidase (GPX), peroxiredoxins (PRDx)

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Depletion of white adipose tissue in cancer cachexia syndrome is associated with inflammatory signaling and disrupted circadian regulation

When growth hormone binds to receptors in muscle, bone, cartilage, and organ tissues, it stimulates protein synthesis, cell proliferation, tissue hypertrophy, and structural growth

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