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In clinical studies, higher levels of circulating long- and medium-chain acylcarnitines showed mixed results in patients with Alzheimers disease [24, 25] whereas clinical trials of patients with Parkinsons disease have consistently shown that circulating levels of long-chain acylcarnitines are decreased [26,27,28]

Fragile X syndrome (FXS) [327] is the most common mutation-based form of intellectual disability Fragile X syndrome (FXS) Its prevalence rate accounts for about 1 in 4000-5000 males and 1 in 6000-8000 females [328, 329]
