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Secretins form a functional channel with an OM pore that is 58 nm wide, allowing the passage of large cargo molecules such as folded proteins and multimeric protein fibers

The threshold for concern is clear, and it's higher than most people assume

10.1038/s41575-019-0258-z 65 LiaoC.SeebeckF

Muscle healing: In models of muscle injury by crushing or transection, the peptide promotes muscle fiber regeneration and reduces scar fibrosis

S8), and the correlation of the localization of PilQ (by immunolabelling) with the nozzles (by electron microscopy) to isolated cross walls or whole cell filaments (compare Fig

and do not occur in intrathylakoidal spaces, carboxysomes, cyanophycin granules, vacuoles, and the periplasm