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Rapid weight loss disrupts this balance

These findings highlight the therapeutic potential of developing novel interventions against specific pathogenic pathways in AS, including chemokine-receptor interactions, immune checkpoint, immunemetabolic modulation, and hormonal/lipid mediator networks, which may collectively overcome the limitations of conventional anti-inflammatory strategies while providing more precise therapeutic effects (230)

Indeed, excitotoxicity, a harmful process in neurons caused by excessive glutamate signaling, leads to neuronal death after injury (Guerriero et al., 2015

In the heart, nothing shows this better than the rapid re-phosphorylation of ADP to ATP by ()

To address this issue, the application of nanocomposites has emerged

Molecular weight provides another difference: peptides possess molecular weights below 5000 Da, whilst proteins exceed this value
