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In: Wilkens K and Juneja V

Comparative Compound Research Used in structureactivity relationship (SAR) studies involving carnitine analogs and related compounds

Awareness of existing contraindications, conditions requiring particular caution, and potential drug interactions enables a more responsible, individualised, and safe approach to patient selection and clinical management

The heterogeneity of the clinical pictures of FM may suggest that different pathophysiological mechanisms, including immune and inflammatory factors, genetic predisposition to small fiber impairments, and mechanisms of central sensitization phenomena, together with psychiatric comorbidities, contribute to the clinical picture of FM [5]

In recent years, new high-tech instruments have changed clinical practice by providing better assessments of tear film quality, tear volume, and meibomian gland function