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Description
Elevated intracellular GSH (or precursors like NAC) in autoimmune conditions has been shown to downregulate the activity of NF-B which mediates pro-inflammatory gene transcription (Limongi et al., 2019)

Ferroptosis and its Role in Diverse Brain Diseases

The pattern is clear: promising preclinical research exists across many domains, but moving from animal models to demonstrated human benefit remains the central scientific challenge
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Annu Rev Pharmacol Toxicol 2007

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