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Mitochondrial dysfunction and damage are implicated in the cognitive decline associated with normal aging as well as in the pathogenesis of most neurodegenerative disorders [126]

However, other studies have shown no evidence of heritability

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Component analysis and previous research strongly suggested that polyphenols contributed to the effects of Amla treatment [29, 30] and that Amla contained various kinds of polyphenols, with gallic acid as a major component [6]
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SUMOylation of Nrf2 at the Neh1 and Neh3 may result in either Nrf2 activation or Nrf2 repression (Silva-Islas and Maldonado, 2018)

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