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Very small volumes of whole blood instead of erythrocytes can be used for the measurement of glutathionine reductase activity, but the method, although simpler, is less sensitive

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Anal Chim Acta 577:7784

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By contrast, GMP-grade FBS undergoes extensive testing for sterility, endotoxins and viral contaminant, whereas unavoidable batch-to-batch variability can still affect reproducibility, thereby increase overall production costs (van der Valk et al., 2018)

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Journal of pharmacology

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