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[DOI] [PubMed] [Google Scholar] 111.Shen L, Turner JR

Hydrolysis-prone sequences Sequences containing asparagine-glycine or glutamine-glycine are particularly vulnerable to deamidation, a base-catalyzed reaction that converts the amide to an acid

However, in a much larger randomized controlled trial of simvastatin and an antioxidant combination of 600 mg of all - rac --tocopherol (297 mg of RRR --tocopherol), 250 mg of vitamin C, and 20 mg of -carotene daily) in more than 20,000 men and women with CHD or diabetes mellitus, the antioxidant combination did not adversely affect the cardioprotective effects of simvastatin therapy over a five-year period (131)

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Oral treatment with -lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial