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2019) and of selenium in DNA biosynthesis or alkyl-hydroperoxide detoxification (Muller et al

259 In addition, the simultaneous knockout of HDAC3, HDAC5, and HDAC7 (class I and class II HDACs) resulted in the CDKN1A (p21) upregulation and inhibition of cell proliferation, 260 similar to p21 induction and cell cycle arrest in human mesenchymal stem cells after drug-induced inhibition of HDAC activity

Disrupting pro-survival and inflammatory pathways with dimethyl fumarate sensitizes chronic lymphocytic leukemia to cell death

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TEM further demonstrated that the knockdown of Bcl-2 could damage the mitochondrial morphology, including spherical swelling, reduced matrix electron density, and disorganized cristae (Figure 4G)

and enzymes such as SOD, CAT, GPx were not among the recommended markers, due to lack of data, representing rather antioxidant than oxidant effects, or due to technical limitations