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At the tissue level, oral pigmentation may involve increased melanin production within basal layer melanocytes, followed by transfer of melanosomes to suprabasal keratinocytes [14,23,24,25]

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The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)

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Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-alpha-lipoic acid