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Thus, the available scientific data on Semax's mechanisms may serve as a reference for the potential pharmacodynamics of N-Acetyl Semax Amidate: Semax enhances Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) levels in the brain, which are neurotrophic factors facilitating neural survival and plasticity

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The electron transport chain (ETC) regulates ferroptosis Mitochondrial ETC activity is not only essential for ATP production but is also required for the generation of sufficient lipid ROS to initiate ferroptosis