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With outstanding advancements in artificial intelligence (AI), it is becoming increasingly clear that AI and machine learning (ML) will play an instrumental role in managing the complexity and dimensionality of microbiome data

108E864E870

Following a detailed analysis of the advantages and limitations associated with nose-to-brain delivery, we consolidate recent advances in nasal nano-delivery systems for treating CNS disorders, emphasizing their capacity to improve brain-targeting efficiency, enhance therapeutic efficacy, reduce systemic toxicity, and enable previously undruggable CNS targets

Besides enhancing UVA protection, DESM can boost the SPF of high-SPF formulations by up to 5 units
doi: 10.1016/j.cell.2011.02.013 46 NunesSCRamosCSantosIMendesCSilvaFVicenteJBet al
In a randomized, single-center, double-blind, placebo-controlled clinical trial, the oral administration of 600 mg/kg ALA twice daily for over 6 months resulted in significant symptomatic improvements in DPN patients
