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27 Our study revealed that some mild adverse events occurred in the first four weeks, although this occurrence was not statistically significant

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10.4049/jimmunol.1201007 176 Makni-MaalejK.MarzaioliV.BoussettaT.BelambriS

The long-term safety profile in humans is not established due to the absence of extended clinical trials

In this way, we can systematically solve the key bottlenecks in the mechanism analysis, therapeutic stability and individualized application of microbial therapies, and promote their advancement from laboratory research to clinical translation, thus opening up a whole new dimension for tumor immunotherapy

At the intersection of methionine metabolism lies S-adenosyl-L-methionine (SAMe), a metabolite of extraordinary biological significance